R41W (p.Arg41Trp) variant of LAMC2 (Laminin subunit gamma-2)
R41W (p.Arg41Trp) in LAMC2 (Laminin subunit gamma-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
R41W (p.Arg41Trp) variant details
- p.Arg41Trp
- cosmic curated COSV99917
- gnomAD rs1658945830
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.04
- CADD 7.83
- PolyPhen-2 0.00
- SIFT 0.23
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available