R41P (p.Arg41Pro) variant of LAMC2 (Laminin subunit gamma-2)
R41P (p.Arg41Pro) in LAMC2 (Laminin subunit gamma-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
R41P (p.Arg41Pro) variant details
- p.Arg41Pro
- TOPMed rs1658945922
- gnomAD rs1658945922
- Missense
- Variant Prioritization Score for Impact Estimate 0.0417
- REVEL 0.03
- CADD 0.75
- PolyPhen-2 0.00
- SIFT 0.32
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available