R35G (p.Arg35Gly) variant of LAMC2 (Laminin subunit gamma-2)
R35G (p.Arg35Gly) in LAMC2 (Laminin subunit gamma-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
R35G (p.Arg35Gly) variant details
- p.Arg35Gly
- Ensembl rs1558084378
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- REVEL 0.13
- CADD 8.77
- PolyPhen-2 0.14
- SIFT 0.14
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available