R25S (p.Arg25Ser) variant of LAMC2 (Laminin subunit gamma-2)
R25S (p.Arg25Ser) in LAMC2 (Laminin subunit gamma-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
R25S (p.Arg25Ser) variant details
- p.Arg25Ser
- gnomAD 1-183186427-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.10
- CADD 15.30
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available