R25M (p.Arg25Met) variant of LAMC2 (Laminin subunit gamma-2)
R25M (p.Arg25Met) in LAMC2 (Laminin subunit gamma-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
R25M (p.Arg25Met) variant details
- p.Arg25Met
- TOPMed rs1658153097
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.20
- CADD 22.40
- PolyPhen-2 0.12
- SIFT 0.07
- Population evidence available
- Structural context available