G32A (p.Gly32Ala) variant of LAMC2 (Laminin subunit gamma-2)
G32A (p.Gly32Ala) in LAMC2 (Laminin subunit gamma-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
G32A (p.Gly32Ala) variant details
- p.Gly32Ala
- ExAC rs776609359
- gnomAD rs776609359
- Missense
- Variant Prioritization Score for Impact Estimate 0.631
- REVEL 0.60
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available