C37Y (p.Cys37Tyr) variant of LAMC2 (Laminin subunit gamma-2)
C37Y (p.Cys37Tyr) in LAMC2 (Laminin subunit gamma-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
C37Y (p.Cys37Tyr) variant details
- p.Cys37Tyr
- 1000Genomes rs551090720
- Missense
- Variant Prioritization Score for Impact Estimate 0.863
- REVEL 0.94
- CADD 25.40
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available