W62R (p.Trp62Arg) variant of LAMB3 (Laminin subunit beta-3)
W62R (p.Trp62Arg) in LAMB3 (Laminin subunit beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
W62R (p.Trp62Arg) variant details
- p.Trp62Arg
- ExAC rs753545651
- gnomAD rs753545651
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.23
- CADD 25.00
- PolyPhen-2 0.98
- SIFT 0.06
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available