S89P (p.Ser89Pro) variant of LAMB3 (Laminin subunit beta-3)
S89P (p.Ser89Pro) in LAMB3 (Laminin subunit beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
S89P (p.Ser89Pro) variant details
- p.Ser89Pro
- TOPMed rs1386179622
- gnomAD rs1386179622
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.37
- CADD 24.20
- PolyPhen-2 0.92
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available