S88F (p.Ser88Phe) variant of LAMB3 (Laminin subunit beta-3)
S88F (p.Ser88Phe) in LAMB3 (Laminin subunit beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
S88F (p.Ser88Phe) variant details
- p.Ser88Phe
- cosmic curated COSV61918
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.36
- CADD 23.70
- PolyPhen-2 0.86
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available