Q73R (p.Gln73Arg) variant of LAMB3 (Laminin subunit beta-3)
Q73R (p.Gln73Arg) in LAMB3 (Laminin subunit beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
Q73R (p.Gln73Arg) variant details
- p.Gln73Arg
- gnomAD rs1270543623
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.12
- AlphaMissense 0.09
- MetaLR 0.16
- MetaSVM -0.97
- CADD 19.00
- PolyPhen-2 0.45
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available