P3Q (p.Pro3Gln) variant of LAMB3 (Laminin subunit beta-3)
P3Q (p.Pro3Gln) in LAMB3 (Laminin subunit beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
P3Q (p.Pro3Gln) variant details
- p.Pro3Gln
- ExAC rs760672832
- TOPMed rs760672832
- gnomAD rs760672832
- Missense
- Variant Prioritization Score for Impact Estimate 0.104
- REVEL 0.05
- CADD 14.80
- PolyPhen-2 0.25
- SIFT 0.07
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available