M92K (p.Met92Lys) variant of LAMB3 (Laminin subunit beta-3)
M92K (p.Met92Lys) in LAMB3 (Laminin subunit beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
M92K (p.Met92Lys) variant details
- p.Met92Lys
- ExAC rs746748625
- TOPMed rs746748625
- gnomAD rs746748625
- Missense
- Variant Prioritization Score for Impact Estimate 0.15
- REVEL 0.20
- CADD 0.40
- PolyPhen-2 0.06
- SIFT 0.95
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available