K65R (p.Lys65Arg) variant of LAMB3 (Laminin subunit beta-3)
K65R (p.Lys65Arg) in LAMB3 (Laminin subunit beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
K65R (p.Lys65Arg) variant details
- p.Lys65Arg
- ESP rs375522351
- ExAC rs375522351
- TOPMed rs375522351
- gnomAD rs375522351
- Missense
- Variant Prioritization Score for Impact Estimate 0.503
- REVEL 0.42
- CADD 24.10
- PolyPhen-2 0.65
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available