G90D (p.Gly90Asp) variant of LAMB3 (Laminin subunit beta-3)
G90D (p.Gly90Asp) in LAMB3 (Laminin subunit beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G90D (p.Gly90Asp) variant details
- p.Gly90Asp
- ExAC rs770169154
- gnomAD rs770169154
- Missense
- Variant Prioritization Score for Impact Estimate 0.468
- REVEL 0.34
- CADD 15.30
- PolyPhen-2 0.09
- SIFT 0.07
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available