G24W (p.Gly24Trp) variant of LAMB3 (Laminin subunit beta-3)
G24W (p.Gly24Trp) in LAMB3 (Laminin subunit beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
G24W (p.Gly24Trp) variant details
- p.Gly24Trp
- ExAC rs750218343
- TOPMed rs750218343
- gnomAD rs750218343
- Missense
- Variant Prioritization Score for Impact Estimate 0.643
- REVEL 0.54
- CADD 27.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available