A86S (p.Ala86Ser) variant of LAMB3 (Laminin subunit beta-3)
A86S (p.Ala86Ser) in LAMB3 (Laminin subunit beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
A86S (p.Ala86Ser) variant details
- p.Ala86Ser
- gnomAD rs1382039871
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.24
- CADD 17.00
- PolyPhen-2 0.15
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available