A10V (p.Ala10Val) variant of LAMB3 (Laminin subunit beta-3)
A10V (p.Ala10Val) in LAMB3 (Laminin subunit beta-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
A10V (p.Ala10Val) variant details
- p.Ala10Val
- gnomAD rs1429374566
- Missense
- Variant Prioritization Score for Impact Estimate 0.134
- REVEL 0.03
- CADD 21.50
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available