V25L (p.Val25Leu) variant of LAMA3 (Laminin subunit alpha-3)
V25L (p.Val25Leu) in LAMA3 (Laminin subunit alpha-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
V25L (p.Val25Leu) variant details
- p.Val25Leu
- TOPMed rs1033783069
- gnomAD rs1033783069
- Missense
- Variant Prioritization Score for Impact Estimate 0.0438
- REVEL 0.02
- CADD 0.05
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available