T35I (p.Thr35Ile) variant of LAMA3 (Laminin subunit alpha-3)
T35I (p.Thr35Ile) in LAMA3 (Laminin subunit alpha-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
T35I (p.Thr35Ile) variant details
- p.Thr35Ile
- TOPMed rs919247921
- gnomAD rs919247921
- Missense
- Variant Prioritization Score for Impact Estimate 0.104
- REVEL 0.01
- CADD 10.10
- PolyPhen-2 0.07
- SIFT 0.17
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available