R6W (p.Arg6Trp) variant of LAMA3 (Laminin subunit alpha-3)
R6W (p.Arg6Trp) in LAMA3 (Laminin subunit alpha-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
R6W (p.Arg6Trp) variant details
- p.Arg6Trp
- TOPMed rs899550243
- gnomAD rs899550243
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- REVEL 0.11
- CADD 21.80
- PolyPhen-2 0.65
- SIFT 0.07
- Population evidence available
- Structural context available