R6G (p.Arg6Gly) variant of LAMA3 (Laminin subunit alpha-3)
R6G (p.Arg6Gly) in LAMA3 (Laminin subunit alpha-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
R6G (p.Arg6Gly) variant details
- p.Arg6Gly
- TOPMed rs899550243
- gnomAD rs899550243
- Missense
- Variant Prioritization Score for Impact Estimate 0.101
- REVEL 0.03
- CADD 13.90
- PolyPhen-2 0.01
- SIFT 0.33
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available