R27P (p.Arg27Pro) variant of LAMA3 (Laminin subunit alpha-3)
R27P (p.Arg27Pro) in LAMA3 (Laminin subunit alpha-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
R27P (p.Arg27Pro) variant details
- p.Arg27Pro
- TOPMed rs1337980671
- gnomAD rs1337980671
- Missense
- Variant Prioritization Score for Impact Estimate 0.0529
- REVEL 0.03
- CADD 3.02
- PolyPhen-2 0.00
- SIFT 0.38
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available