R10W (p.Arg10Trp) variant of LAMA3 (Laminin subunit alpha-3)
R10W (p.Arg10Trp) in LAMA3 (Laminin subunit alpha-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
R10W (p.Arg10Trp) variant details
- p.Arg10Trp
- TOPMed rs2060541573
- Missense
- Variant Prioritization Score for Impact Estimate 0.052
- REVEL 0.02
- CADD 5.24
- PolyPhen-2 0.00
- SIFT 0.23
- Population evidence available
- Structural context available