R10P (p.Arg10Pro) variant of LAMA3 (Laminin subunit alpha-3)
R10P (p.Arg10Pro) in LAMA3 (Laminin subunit alpha-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R10P (p.Arg10Pro) variant details
- p.Arg10Pro
- TOPMed rs1014633904
- gnomAD rs1014633904
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.05
- CADD 22.70
- PolyPhen-2 0.62
- SIFT 0.22
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available