A4D (p.Ala4Asp) variant of LAMA3 (Laminin subunit alpha-3)
A4D (p.Ala4Asp) in LAMA3 (Laminin subunit alpha-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
A4D (p.Ala4Asp) variant details
- p.Ala4Asp
- TOPMed rs1372314794
- gnomAD rs1372314794
- Missense
- Variant Prioritization Score for Impact Estimate 0.149
- REVEL 0.03
- CADD 17.00
- PolyPhen-2 0.02
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available