R59G (p.Arg59Gly) variant of KRT9 (Keratin, type I cytoskeletal 9)
R59G (p.Arg59Gly) in KRT9 (Keratin, type I cytoskeletal 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
R59G (p.Arg59Gly) variant details
- p.Arg59Gly
- ExAC rs747867129
- TOPMed rs747867129
- gnomAD rs747867129
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.44
- CADD 6.84
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available