L86S (p.Leu86Ser) variant of KRT9 (Keratin, type I cytoskeletal 9)
L86S (p.Leu86Ser) in KRT9 (Keratin, type I cytoskeletal 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L86S (p.Leu86Ser) variant details
- p.Leu86Ser
- Ensembl rs1907092987
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.37
- CADD 7.56
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available