G76R (p.Gly76Arg) variant of KRT9 (Keratin, type I cytoskeletal 9)
G76R (p.Gly76Arg) in KRT9 (Keratin, type I cytoskeletal 9) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
G76R (p.Gly76Arg) variant details
- p.Gly76Arg
- rs1317930682
- TOPMed rs1317930682
- gnomAD rs1317930682
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.38
- CADD 11.20
- PolyPhen-2 0.17
- SIFT 0.09
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available