G25R (p.Gly25Arg) variant of KRT9 (Keratin, type I cytoskeletal 9)
G25R (p.Gly25Arg) in KRT9 (Keratin, type I cytoskeletal 9) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G25R (p.Gly25Arg) variant details
- p.Gly25Arg
- rs762726903
- NCI-TCGA Cosmic COSV5585
- ExAC rs762726903
- gnomAD rs762726903
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.22
- CADD 9.45
- PolyPhen-2 0.02
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available