G109W (p.Gly109Trp) variant of KRT9 (Keratin, type I cytoskeletal 9)
G109W (p.Gly109Trp) in KRT9 (Keratin, type I cytoskeletal 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
G109W (p.Gly109Trp) variant details
- p.Gly109Trp
- ExAC rs775247961
- gnomAD rs775247961
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.49
- CADD 18.80
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available