C61W (p.Cys61Trp) variant of KRT9 (Keratin, type I cytoskeletal 9)
C61W (p.Cys61Trp) in KRT9 (Keratin, type I cytoskeletal 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
C61W (p.Cys61Trp) variant details
- p.Cys61Trp
- ExAC rs780777859
- TOPMed rs780777859
- gnomAD rs780777859
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.49
- CADD 21.70
- PolyPhen-2 0.75
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available