C61S (p.Cys61Ser) variant of KRT9 (Keratin, type I cytoskeletal 9)
C61S (p.Cys61Ser) in KRT9 (Keratin, type I cytoskeletal 9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
C61S (p.Cys61Ser) variant details
- p.Cys61Ser
- TOPMed rs1340627837
- gnomAD rs1340627837
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.20
- CADD 6.31
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available