V66I (p.Val66Ile) variant of KRT8 (Keratin, type II cytoskeletal 8)
V66I (p.Val66Ile) in KRT8 (Keratin, type II cytoskeletal 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data.
V66I (p.Val66Ile) variant details
- p.Val66Ile
- ExAC rs766537083
- gnomAD rs766537083
- Missense
- Variant Prioritization Score for Impact Estimate 0.521
- CADD 17.40
- PolyPhen-2 0.01
- SIFT 0.17
- Most common in the South Asian population (allele frequency 1.2e-05)