S35T (p.Ser35Thr) variant of KRT8 (Keratin, type II cytoskeletal 8)
S35T (p.Ser35Thr) in KRT8 (Keratin, type II cytoskeletal 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S35T (p.Ser35Thr) variant details
- p.Ser35Thr
- ExAC rs758703720
- gnomAD rs758703720
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- CADD 21.90
- PolyPhen-2 0.06
- SIFT 0.12
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available