S24Y (p.Ser24Tyr) variant of KRT8 (Keratin, type II cytoskeletal 8)
S24Y (p.Ser24Tyr) in KRT8 (Keratin, type II cytoskeletal 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data.
S24Y (p.Ser24Tyr) variant details
- p.Ser24Tyr
- ExAC rs774320109
- TOPMed rs774320109
- gnomAD rs774320109
- Missense
- Variant Prioritization Score for Impact Estimate 0.763
- CADD 25.50
- PolyPhen-2 0.59
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)