R110W (p.Arg110Trp) variant of KRT8 (Keratin, type II cytoskeletal 8)
R110W (p.Arg110Trp) in KRT8 (Keratin, type II cytoskeletal 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data.
R110W (p.Arg110Trp) variant details
- p.Arg110Trp
- ESP rs145511223
- ExAC rs145511223
- gnomAD rs145511223
- Missense
- Variant Prioritization Score for Impact Estimate 0.371
- CADD 24.10
- PolyPhen-2 0.08
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)