Q85E (p.Gln85Glu) variant of KRT8 (Keratin, type II cytoskeletal 8)
Q85E (p.Gln85Glu) in KRT8 (Keratin, type II cytoskeletal 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
Q85E (p.Gln85Glu) variant details
- p.Gln85Glu
- 1000Genomes rs532491388
- ExAC rs532491388
- gnomAD rs532491388
- Missense
- Variant Prioritization Score for Impact Estimate 0.733
- CADD 24.40
- PolyPhen-2 0.12
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available