P82S (p.Pro82Ser) variant of KRT8 (Keratin, type II cytoskeletal 8)
P82S (p.Pro82Ser) in KRT8 (Keratin, type II cytoskeletal 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
P82S (p.Pro82Ser) variant details
- p.Pro82Ser
- TOPMed rs1380444038
- Missense
- Variant Prioritization Score for Impact Estimate 0.553
- CADD 25.90
- PolyPhen-2 0.84
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available