N69S (p.Asn69Ser) variant of KRT8 (Keratin, type II cytoskeletal 8)
N69S (p.Asn69Ser) in KRT8 (Keratin, type II cytoskeletal 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data.
N69S (p.Asn69Ser) variant details
- p.Asn69Ser
- cosmic curated COSV10512
- ExAC rs773747000
- TOPMed rs773747000
- gnomAD rs773747000
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- CADD 23.30
- PolyPhen-2 0.12
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)