N116K (p.Asn116Lys) variant of KRT8 (Keratin, type II cytoskeletal 8)
N116K (p.Asn116Lys) in KRT8 (Keratin, type II cytoskeletal 8) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data.
N116K (p.Asn116Lys) variant details
- p.Asn116Lys
- NCI-TCGA Cosmic COSV5317
- cosmic curated COSV53178
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- CADD 24.60
- PolyPhen-2 0.97
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available