D81N (p.Asp81Asn) variant of KRT8 (Keratin, type II cytoskeletal 8)
D81N (p.Asp81Asn) in KRT8 (Keratin, type II cytoskeletal 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
D81N (p.Asp81Asn) variant details
- p.Asp81Asn
- gnomAD rs1202340708
- Missense
- Variant Prioritization Score for Impact Estimate 0.579
- CADD 24.40
- PolyPhen-2 0.16
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available