A65T (p.Ala65Thr) variant of KRT8 (Keratin, type II cytoskeletal 8)
A65T (p.Ala65Thr) in KRT8 (Keratin, type II cytoskeletal 8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data.
A65T (p.Ala65Thr) variant details
- p.Ala65Thr
- ExAC rs759804104
- TOPMed rs759804104
- gnomAD rs759804104
- Missense
- Variant Prioritization Score for Impact Estimate 0.26
- CADD 14.40
- PolyPhen-2 0.04
- SIFT 0.18
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)