Y83N (p.Tyr83Asn) variant of KRT6B (Keratin, type II cytoskeletal 6B)
Y83N (p.Tyr83Asn) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
Y83N (p.Tyr83Asn) variant details
- p.Tyr83Asn
- gnomAD rs1175394022
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.25
- CADD 17.10
- PolyPhen-2 0.04
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available