T6N (p.Thr6Asn) variant of KRT6B (Keratin, type II cytoskeletal 6B)
T6N (p.Thr6Asn) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
T6N (p.Thr6Asn) variant details
- p.Thr6Asn
- ExAC rs764803667
- TOPMed rs764803667
- gnomAD rs764803667
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.09
- CADD 22.50
- PolyPhen-2 0.48
- SIFT 0.03
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available