S41P (p.Ser41Pro) variant of KRT6B (Keratin, type II cytoskeletal 6B)
S41P (p.Ser41Pro) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
S41P (p.Ser41Pro) variant details
- p.Ser41Pro
- Ensembl rs1940414257
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.30
- CADD 21.70
- PolyPhen-2 0.15
- SIFT 0.04
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available