S35N (p.Ser35Asn) variant of KRT6B (Keratin, type II cytoskeletal 6B)
S35N (p.Ser35Asn) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S35N (p.Ser35Asn) variant details
- p.Ser35Asn
- gnomAD rs1341343109
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.13
- CADD 18.20
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available