R59H (p.Arg59His) variant of KRT6B (Keratin, type II cytoskeletal 6B)
R59H (p.Arg59His) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R59H (p.Arg59His) variant details
- p.Arg59His
- ExAC rs771831330
- TOPMed rs771831330
- gnomAD rs771831330
- Missense
- Variant Prioritization Score for Impact Estimate 0.232
- REVEL 0.12
- CADD 21.90
- PolyPhen-2 0.04
- SIFT 0.04
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available