R15S (p.Arg15Ser) variant of KRT6B (Keratin, type II cytoskeletal 6B)
R15S (p.Arg15Ser) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
R15S (p.Arg15Ser) variant details
- p.Arg15Ser
- ExAC rs772519522
- TOPMed rs772519522
- gnomAD rs772519522
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.07
- CADD 22.00
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available