P26L (p.Pro26Leu) variant of KRT6B (Keratin, type II cytoskeletal 6B)
P26L (p.Pro26Leu) in KRT6B (Keratin, type II cytoskeletal 6B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
P26L (p.Pro26Leu) variant details
- p.Pro26Leu
- TOPMed rs1454903643
- gnomAD rs1454903643
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.23
- CADD 23.60
- PolyPhen-2 0.04
- SIFT 0.03
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available